Synthetic peptide with sequence C-QPFDFPDDNQNSKK, corresponding to internal sequence amino acids 333 - 346 of Human Connexin 43/ GJA1, with a Cysteine residue linker (NP_000156.1.)
Conjugate
Unconjugated
Applications
Application Notes
WB: 0.3 - 1 μg/ml; IHC-P: 1 μg/ml;
Target
Alternative Names
GJA1; gap junction protein, alpha 1, 43kDa; HSS; CMDR; CX43; GJAL; ODDD; AVSD3; HLHS1; gap junction alpha-1 protein; connexin 43; connexin-43; gap junction 43 kDa heart protein;
One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. May play a critical role in the physiology of hearing by participating in the recycling of potassium to the cochlear endolymph.
Pathway
Arrhythmogenic right ventricular cardiomyopathy; Arrhythmogenic right ventricular cardiomyopathy (ARVC); Corticotropin-releasing hormone; Formation of annular gap junctions
Citations
Publication ()
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