CASP6 blocking peptide (DAG-P1402)

Synthetic CASP6 blocking peptide for WB, BL Datasheet

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Nature
Synthetic
Tag/Conjugate
Unconjugated
Sequence Similarities
Belongs to the peptidase C14A family.
Cellular Localization
Cytoplasm.
Format
Liquid
Buffer
Preservative: 0.02% Thimerosal (merthiolate) Constituents: 0.1% BSA, PBS, pH 7.2
Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles. Preservative: 0.02% Thimerosal (merthiolate) Constituents: 0.1% BSA, PBS, pH 7.2
UniProt ID
Antigen Description
This gene encodes a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This protein is processed by caspases 7, 8 and 10, and is thought to function as a downstream enzyme in the caspase activation cascade. Alternative splicing of this gene results in two transcript variants that encode different isoforms. [provided by RefSeq, Jul 2008]
Function
cysteine-type endopeptidase activity; cysteine-type endopeptidase activity; cysteine-type peptidase activity; identical protein binding; protein binding;
Synonyms
CASP6; caspase 6, apoptosis-related cysteine peptidase; MCH2; caspase-6; apoptotic protease MCH-2; caspase 6, apoptosis-related cysteine protease;

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