Human CNOT4 blocking peptide (CDBP0837)

Synthetic Human CNOT4 blocking peptide for BL

Product Overview
Blocking peptide for anti-CNOT4 antibody
Target
CNOT4
Nature
Synthetic
Species Reactivity
Human
Tag/Conjugate
Unconjugated
Application Notes
For in vitro research use only. Not intended for any diagnostic or therapeutic purpose. Not suitable for human or animal consumption.
Procedure
None
Format
Liquid
Concentration
200 μg/ml
Size
50 μg
Buffer
PBS containing 0.02% sodium azide
Preservative
0.02% Sodium Azide
Storage
Store at -20℃, stable for one year.
UniProt ID
Antigen Description
The protein encoded by this gene is a subunit of the CCR4-NOT complex, a global transcriptional regulator. The encoded protein interacts with CNOT1 and has E3 ubiquitin ligase activity. Several transcript variants encoding different isoforms have been found for this gene.
Function
RNA binding; ligase activity; metal ion binding; nucleotide binding; protein binding; ubiquitin-protein ligase activity; zinc ion binding;
Synonyms
CNOT4; CCR4-NOT transcription complex, subunit 4; NOT4; CCR4-NOT transcription complex subunit 4; CLONE243; NOT4H; CCR4-associated factor 4; E3 ubiquitin-protein ligase CNOT4; potential transcriptional repressor NOT4Hp; NOT4 (negative regulator of transcription 4, yeast) homolog;

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References


Laribee, RN; Shibata, Y; et al. CCR4/NOT complex associates with the proteasome and regulates histone methylation. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 104:5836-5841(2007).
Mulder, KW; Winkler, GS; et al. DNA damage and replication stress induced transcription of RNR genes is dependent on the Ccr4-Not complex. NUCLEIC ACIDS RESEARCH 33:6384-6392(2005).

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