Human CBL ELISA Matched Antibody Pair

Name: Human CBL ELISA Matched Antibody Pair
SKU: ABPR-0148
Rating: 5 (1 reviews)

Regulatory status: For research use only, not for use in diagnostic procedures.

COA

SDS

Datasheet

Summary

Species Reactivity

Human

Intended Use

This antibody pair set comes with matched antibody pair to detect and quantify protein level of human CBL.

General Description

This gene is a proto-oncogene that encodes a RING finger E3 ubiquitin ligase. The encoded protein is one of the enzymes required for targeting substrates for degradation by the proteasome. This protein mediates the transfer of ubiquitin from ubiquitin conjugating enzymes (E2) to specific substrates. This protein also contains an N-terminal phosphotyrosine binding domain that allows it to interact with numerous tyrosine-phosphorylated substrates and target them for proteasome degradation. As such it functions as a negative regulator of many signal transduction pathways. This gene has been found to be mutated or translocated in many cancers including acute myeloid leukaemia. Mutations in this gene are also the cause of Noonan syndrome-like disorder.

Reconstitution And Storage

Store reagents of the antibody pair set at -20°C or lower. Please aliquot to avoid repeated freeze thaw cycle. Reagents should be returned to -20°C storage immediately after use.

Citations

Have you cited ABPR-0148 in a publication? Let us know and earn a reward for your research.

Documents

pdf COA

pdf SDS

pdf Datasheet

QA & Reviews

Customer Reviews

References

Dual-functional cathode buffer layer for power conversion efficiency enhancement of bulk-heterojunction solar cells

SYNTHETIC METALS

Authors: Datt, Ram; Bishnoi, Swati; Gupta, Ramashanker; Haranath, D.; Sharma, Shailesh N.; Gupta, Govind; Arya, Sandeep; Kumar, S.; Gupta, Vinay

Abstract

Here, we report a luminescent cathode buffer layer (CBL) for power conversion efficiency (PCE) enhancement of organic solar cells (OSCs). ZnO doped with Aluminum (Al) and Europium (Eu) was cast as CBL by a solution-processed method. CBL serves a dual purpose by acting both as a spectral conversion and an electron transporting layer. The luminescent ZnO:Al,Eu CBL layer has broad absorption spanning the ultraviolet (300-400 nm) spectrum, contributing to absorption enhancement. Moreover, the emission of CBL layer overlaps with the absorption of poly [N -9'-heptadecanyl-2,7-carbazole- alt-5,5-(4',7'-di-2-thienyl-2',1',3'-benzothiadiazole)] (PCDTBT) polymer thus elevating the overall absorption of the active layer and improving the photocurrent With this ZnO:Al,Eu CBL in the inverted device configuration (ITO/CBL/active layer/MoOx/Al), an enhanced power conversion efficiency (PCE) of 6.9% was obtained while the device with pristine ZnO as CBL showed PCE of 5.9%. A blend of PCDTBT donor and [6,6]-phenyl C-71 butyric acid methyl ester (PC71BM) acceptor was used as an active layer in both the cases. In ZnO:Al,Eu CBL layer, Al doping improves the conductivity, while Eu doping significantly enhances the emission in the visible region by down-shifting the incoming solar UV light to the visible range which overlaps with the absorption of PCDTBT polymer resulting in energy transfer and improved overall device efficiency. The findings of the study show the significance of luminescent znO:ALEu nanoparticle CBL in enhancing the performance of organic solar cells.

Development of Case-Based Learning (CBL) in Engineering Technology Education

INTERNATIONAL JOURNAL OF ENGINEERING EDUCATION

Authors: Alani, Faiez

Abstract

Case-based learning (CBL) is an active learning technique that has traditionally been underutilized in engineering technology education research. Real-life case studies were developed and used in teaching and learning two biotechnology courses in winter 2019. The overall student evaluation of CBL was positive: 71% of students agreed that CBL enhanced their learning, while 13% disagreed and 16% of students were neutral. 74% of students found that CBL helped them in team working skill and 24% were neutral. Detailed evaluation and discussion of CBL enhancement on problem solving, critical thinking, learning experience and technical skills are carried out in this study.