Synthetic Human BACE2 blocking peptide for BL
BACE 2 ( N - term ) peptide ( human )
PBS with 0.1% BSA 0.02% sodium azide pH7.2
Upon Receipt - Keep as concentrated solution. Aliquot and store at -20oC or below. Avoid freeze-thaw cycles.
This gene encodes an integral membrane glycoprotein that functions as an aspartic protease. The encoded protein cleaves amyloid precursor protein into amyloid beta peptide, which is a critical step in the etiology of Alzheimer's disease and Down syndrome. The protein precursor is further processed into an active mature peptide. Alternative splicing results in multiple transcript variants.
aspartic-type endopeptidase activity; peptidase activity;
BACE2; beta-site APP-cleaving enzyme 2; AEPLC; beta-secretase 2; ALP56; CEAP1; DRAP; asp 1; memapsin-1; theta-secretase; beta secretase 2; aspartyl protease 1; 56 kDa aspartic-like protease; aspartic-like protease 56 kDa; down region aspartic protease; beta-site APP cleaving enzyme 2; Down syndrome region aspartic protease; transmembrane aspartic proteinase Asp1; membrane-associated aspartic protease 1; beta-site amyloid precursor protein cleaving enzyme 2; beta-site amyloid beta A4 precursor protein-cleaving enzyme 2; ASP1; BAE2; ASP21; CDA13;