Anti-BACE2 monoclonal antibody Made to order

Antibody Isotype

IgG

Species Reactivity

Human

Immunogen

A synthetic peptide of human BACE2 is used for rabbit immunization.

Conjugate

Unconjugated

Alternative Names

BACE2; beta-site APP-cleaving enzyme 2; AEPLC; beta-secretase 2; ALP56; CEAP1; DRAP; asp 1; memapsin-1; theta-secretase; beta secretase 2; aspartyl protease 1; 56 kDa aspartic-like protease; aspartic-like protease 56 kDa; down region aspartic protease; be

Entrez Gene ID

25825

UniProt ID

Q9Y5Z0

Antigen Description

Cerebral deposition of amyloid beta peptide is an early and critical feature of Alzheimers disease and a frequent complication of Down syndrome. Amyloid beta peptide is generated by proteolytic cleavage of amyloid precursor protein by 2 proteases, one of which is the protein encoded by this gene. This gene localizes to the Down critical region of chromosome 21. The encoded protein, a member of the peptidase A1 protein family, is a type I integral membrane glycoprotein and aspartic protease. Three transcript variants encoding different isoforms have been described for this gene.

Pathway

Alzheimers disease, organism-specific biosystem; Alzheimers disease, conserved biosystem;

We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody. Learn More