Anti-ssDNA monoclonal antibody (DMAB23910)

Mouse anti-Bovine ssDNA monoclonal antibody for FC, IHC Datasheet

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Alternative Names
Singal strand DNA; Mouse Anti-ssDNA Monoclonal Antibody; Anti-ssDNA Monoclonal Antibody; ssDNA Monoclonal Antibody Mouse Anti-ssDNA MAb; Anti-ssDNA MAb; ssDNA MAb

Product Background

Antigen Description
most DNA molecules are actually two polymer strands, bound together in a helical fashion by noncovalent bonds; this double stranded structure (dsDNA) is maintained largely by the intrastrand base stacking interactions, which are strongest for G,C stacks. The two strands can come apart – a process known as melting – to form two ssDNA molecules. Melting occurs when conditions favor ssDNA; such conditions are high temperature, low salt and high pH (low pH also melts DNA, but since DNA is unstable due to acid depurination, low pH is rarely used).


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Sato, S; Fujimoto, M; et al. Soluble CD4 and CD8 in serum from patients with localized scleroderma. ARCHIVES OF DERMATOLOGICAL RESEARCH 288:358-362(1996).
Zhang, J; Williams, N; et al. Purification, cloning, and expression of two closely related Trypanosoma brucei nucleic acid binding proteins. MOLECULAR AND BIOCHEMICAL PARASITOLOGY 87:145-158(1997).

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