Mouse anti-Vancomycin monoclonal antibody for IA
Until recently, Vancomycin was one of the most powerful antibiotics that no bacterial cell had resistance to. Vancomycin is a very successful glycopeptide antibiotic, attacking the D alanyl D alanine component of the cell wall. By binding to the D alanyl D alanine component, Vancomycin is able to interrupt the normal cell wall formation. However, recently cells have achieved resistance to vancomycin. The reason that the resistance is so effective is that these cells have modified the D alanyl D alanine components of the cell wall into D alanyl D lactate components. Although this may sound easy, the actual process involves a series of five or more genes.
Ericson, JE; Thaden, J; et al. No Survival Benefit With Empirical Vancomycin Therapy for Coagulase-negative Staphylococcal Bloodstream Infections in Infants. PEDIATRIC INFECTIOUS DISEASE JOURNAL 34:371-375(2015).
Loca, D; Sokolova, M; et al. Calcium phosphate bone cements for local vancomycin delivery. MATERIALS SCIENCE & ENGINEERING C-MATERIALS FOR BIOLOGICAL APPLICATIONS 49:106-113(2015).
Custom Antibody Labeling
We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody.