Specificity: TLE4 Antibody detects endogenous levels of total TLE4.
Host: Rabbit
Application: WB, IF/ICC
Species Reactivity: Human; Predicted: Bovine, Horse, Sheep, Rabbit, Dog, Xenopus
Summary
Specifications
Antibody Isotype
IgG
Species Reactivity
Human
Immunogen
A synthesized peptide derived from human TLE4, corresponding to a region within the internal amino acids.
Conjugate
Unconjugated
Applications
Application Notes
WB 1:1000 IF/ICC 1:100-1:500
General Notes
This product (Catalog No. DPABH-28637) is a rabbit-derived polyclonal antibody raised against human TLE4. It has been affinity purified by Protein A. Transcriptional corepressor that binds to a number of transcription factors. Inhibits the transcriptional activation mediated by PAX5, and by CTNNB1 and TCF family members in Wnt signaling. The effects of full-length TLE family members may be modulated by association with dominant-negative AES. Essential for the transcriptional repressor activity of SIX3 during retina and lens development and for SIX3 transcriptional auto-repression (By similarity). DPABH-28637 is suitable for use in WB 1 (1000), IF/ICC 1 (100-1:500) applications. DPABH-28637 is supplied as a liquid formulation in Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. For long-term storage, keep at −20 °C. For short-term use, store at 2–8 °C. Avoid repeated freeze–thaw cycles to maintain antibody integrity and performance.
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