Anti-TIMP1 polyclonal antibody (CPBT-65286RH)

Rabbit anti-Human TIMP1 polyclonal antibody for ELISA, IHC-P, WB

Specifications


Host Species
Rabbit
Antibody Isotype
IgG
Species Reactivity
Human, Bovine, Ferret, Horse, Rabbit, Rat, Sheep
Immunogen
Human tissue inhibitor of metalloproteinase 1 (TIMP-1)
Conjugate
Unconjugated

Applications


Application Notes
Immunohistology - Paraffin: 1 - 5ug/ml; ELISA: 2.5 - 10ug/ml; Western Blot: 5 - 10ug/ml;
*Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own experiment using appropriate negative and positive controls.

Target


Alternative Names
TIMP1; TIMP metallopeptidase inhibitor 1; EPA; EPO; HCI; CLGI
Entrez Gene ID
UniProt ID
P01033

Product Background


Pathway
Activation of Matrix Metalloproteinases; Degradation of the extracellular matrix; Extracellular matrix organization; HIF-1 signaling pathway; Hemostasis; IL6-mediated signaling events; Matrix Metalloproteinases; Platelet activation, signaling and aggregation;

Citations


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Custom Antibody Labeling


We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody. Learn More

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References


Li, MQ; Hou, XF; et al. The DSCs-Expressed CD82 Controls the Invasiveness of Trophoblast Cells via Integrinbeta1/MAPK/MAPK3/1 Signaling Pathway in Human First-Trimester Pregnancy. BIOLOGY OF REPRODUCTION 82:968-979(2010).
Pellegrini, P; Contasta, I; et al. Simultaneous measurement of soluble carcinoembryonic antigen and the tissue inhibitor of metalloproteinase TIMP1 serum levels for use as markers of pre-invasive to invasive colorectal cancer. CANCER IMMUNOLOGY IMMUNOTHERAPY 49:388-394(2000).

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