Anti-TIMP1 polyclonal antibody (CPBT-65286RH)

Rabbit anti-Human TIMP1 polyclonal antibody for ELISA, IHC-P, WB

Specifications


Host Species
Rabbit
Antibody Isotype
IgG
Species Reactivity
Human, Bovine, Ferret, Horse, Rabbit, Rat, Sheep
Immunogen
Human tissue inhibitor of metalloproteinase 1 (TIMP-1)
Conjugate
Unconjugated

Applications


Application Notes
Immunohistology - Paraffin: 1 - 5ug/ml; ELISA: 2.5 - 10ug/ml; Western Blot: 5 - 10ug/ml;
*Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own experiment using appropriate negative and positive controls.

Target


Alternative Names
TIMP1; TIMP metallopeptidase inhibitor 1; EPA; EPO; HCI; CLGI
Entrez Gene ID
UniProt ID
P01033

Product Background


Pathway
Activation of Matrix Metalloproteinases; Degradation of the extracellular matrix; Extracellular matrix organization; HIF-1 signaling pathway; Hemostasis; IL6-mediated signaling events; Matrix Metalloproteinases; Platelet activation, signaling and aggregation;

Citations


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Custom Antibody Labeling


We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody. Learn More

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References


Van den Eynden, GG; Van Laere, SJ; et al. Differential expression of hypoxia and (lymph)angiogenesis-related genes at different metastatic sites in breast cancer. CLINICAL & EXPERIMENTAL METASTASIS 24:13-23(2007).
Liu, YD; Brymora, J; et al. Leptin and Acetaldehyde Synergistically Promotes alpha SMA Expression in Hepatic Stellate Cells by an Interleukin 6-Dependent Mechanism. ALCOHOLISM-CLINICAL AND EXPERIMENTAL RESEARCH 35:921-928(2011).

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