Alternative Names
Tissue Inhibitor of Metalloproteinases 1; TIMP-1; Metalloproteinase Inhibitor 1
Purity
> 95% , as determined by SDS-PAGE
Concentration
Batch dependent - please inquire should you have specific requirements.
Storage
Store at -20°C to -80°C
Introduction
TIMP metallopeptidase inhibitor 1, also known as TIMP1, a tissue inhibitor of metalloproteinases, is a glycoprotein that is expressed from several tissues of organisms. This protein is a member of the TIMP family. The glycoprotein is a natural inhibitor of the matrix metalloproteinases (MMPs), a group of peptidases involved in degradation of the extracellular matrix. In addition to its inhibitory role against most of the known MMPs, the encoded protein is able to promote cell proliferation in a wide range of cell types, and may also have an anti-apoptotic function.
Antigen Description
Recombinant Human Tissue Inhibitor of Metalloproteinases 1 (TIMP-1) is produced by Mammalian expression system and the target gene encoding Cys24-Ala207 is expressed with a 6His tag at the C-terminus.
Keywords
TIMP metallopeptidase inhibitor 1; TIMP1; Matrix metalloproteinases
Citations
Publication ()
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