TIRP is a Toll/interleukin-1 receptor (IL1R; MIM 147810) (TIR) domain-containing adaptor protein involved in Toll receptor signaling (see TLR4; MIM 603030).[supplied by OMIM, Apr 2004]
Pathway
Activated TLR4 signalling; Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon; Hepatitis B; IKK complex recruitment mediated by RIP1; IL1-mediated signaling events; Immune System; Innate Immune System; MyD88-independent cascade
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