General Notes
This product (Catalog No. DPABH-09644) is a rabbit-derived polyclonal antibody raised against human TICAM2. This antibody exhibits cross-reactivity with Human TICAM2 from mouse. It has been affinity purified by Protein A. TICAM2, also named TIRAP3, TIRP, and TRAM, is involved in IL1-triggered NF-kappa-B activation, functioning upstream of IRAK1, IRAK2, TRAF6, and IKBKB. Physically bridges TLR4 and TICAM1 and functionally transmits LPS-TRL4 signal to TICAM1. TICAM2 is involved in LPS-TLR4 signaling to regulate the MYD88-independent pathway during the innate immune response to LPS.In WB, the MW of TICAM2 is about 27-32 kDa.
DPABH-09644 is suitable for use in Western blot (WB) (1:500–1:1,000), IHC (1:50–1:500) applications.
DPABH-09644 is supplied as a liquid formulation in PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. For long-term storage, keep at −20 °C. For short-term use, store at 2–8 °C. Avoid repeated freeze–thaw cycles to maintain antibody integrity and performance.
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