Anti-SUMO2 (C-terminal) polyclonal antibody

Antibody Isotype

IgG

Species Reactivity

Human

Immunogen

SUMO2/3 antibody was raised against a 15 amino acid peptide near the carboxy terminus of human SUMO2.

Conjugate

Alternative Names

SUMO2; small ubiquitin-like modifier 2; HSMT3; SMT3B; SUMO3; Smt3A; SMT3H2; small ubiquitin-related modifier 2; sentrin 2; SMT3 homolog 2; ubiquitin-like protein SMT3A; ubiquitin-like protein SMT3B; SMT3 suppressor of mif two 3 homolog 2

Entrez Gene ID

UniProt ID

Antigen Description

This gene encodes a protein that is a member of the SUMO (small ubiquitin-like modifier) protein family. It functions in a manner similar to ubiquitin in that it is bound to target proteins as part of a post-translational modification system. However, unlike ubiquitin which targets proteins for degradation, this protein is involved in a variety of cellular processes, such as nuclear transport, transcriptional regulation, apoptosis, and protein stability. It is not active until the last two amino acids of the carboxy-terminus have been cleaved off. Numerous pseudogenes have been reported for this gene. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008]

Pathway

Glucocorticoid receptor regulatory network; Metabolism of proteins; Nuclear pore complex; Post-translational protein modification; Processing and activation of SUMO; RNA transport; SUMO is conjugated to E1 (UBA2:SAE1); SUMO is proteolytically processed