Anti-SUMO2 (full length) polyclonal antibody

Species Reactivity

Human

Immunogen

SUMO2 (AAH08450, 1 a.a. ~ 95 a.a) full-length recombinant protein with GST tag. The sequence is MADEKPKEGVKTENNNHINLKVAGQDGSVVQFKIKRHTPLSKLMKAYCERQGLSMRQIRF RFDGQPINETDTPAQLEMEDEDTIDVFQQQTGGVY

Conjugate

Alternative Names

SUMO2; small ubiquitin-like modifier 2; HSMT3; SMT3B; SUMO3; Smt3A; SMT3H2; small ubiquitin-related modifier 2; sentrin 2; SMT3 homolog 2; ubiquitin-like protein SMT3A; ubiquitin-like protein SMT3B; SMT3 suppressor of mif two 3 homolog 2;

Entrez Gene ID

UniProt ID

Antigen Description

This gene encodes a protein that is a member of the SUMO (small ubiquitin-like modifier) protein family. It functions in a manner similar to ubiquitin in that it is bound to target proteins as part of a post-translational modification system. However, unlike ubiquitin which targets proteins for degradation, this protein is involved in a variety of cellular processes, such as nuclear transport, transcriptional regulation, apoptosis, and protein stability. It is not active until the last two amino acids of the carboxy-terminus have been cleaved off. Numerous pseudogenes have been reported for this gene. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.

Pathway

Glucocorticoid receptor regulatory network; Nuclear pore complex; Post-translational protein modification; RNA transport