Metallurgical slag properties as a support material for bimetallic nanoparticles and their use in the removal of malachite green dye
ADVANCED POWDER TECHNOLOGY
Authors: Blanco-Flores, Alien; Toledo-Jaldin, Helen P.; Vilchis-Nestor, Alfredo R.; Lopez-Tellez, Gustavo; Sanchez-Mendieta, Victor; Avila-Marquez, Delia M.
Abstract
Fe-Cu oxides nanoparticles (Nps) were embedded in two steel slag wastes (SSB and SSW) to develop SSB/Fe-Cu and SSW/Fe-Cu nanocomposites. Nps with mean sizes between 10-20 and 6-10 nm on SSW and SSB, respectively are agglomeration with a different shape. Their characteristics were investigated by XRD, TEM, BET, SEM techniques. The Nps modified the morphology of both support materials. XRD pointed out the presence of Cu and Fe. The proportion of Cu concentration was higher than the one of Fe. Nanocomposites were tested in malachite green removal from aqueous solution. The adsorption kinetic indicated physisorption and chemisorption as the main mechanisms of adsorption. The adsorption capacities were 88.26 and 63.55 mg/g for SSW/Fe-Cu and SSB/Fe-Cu, respectively. This novel, easy to prepare and low-cost nanocomposites is an efficient adsorbent material. The presence of calcium compounds may improve Nps deposition an MG removal. Materials with ferric phases are not as efficient as the first one; Fe is not well supported on the material. The removal of MG took place by dye structure modification and by interactions with Cu nanoparticles improving the oxidation-reduction process, through synergic effects. (C) 2020 The Society of Powder Technology Japan. Published by Elsevier B.V. and The Society of Powder Technology Japan. All rights reserved.
Hydroxychloroquine is associated with a lower risk of polyautoimmunity: data from the RELESSER Registry
RHEUMATOLOGY
Authors: Mena-Vazquez, Natalia; Fernandez-Nebro, Antonio; Maria Pego-Reigosa, Jose; Galindo, Maria; Melissa-Anzola, Ana; Uriarte-Isacelay, Esther; Olive-Marques, Alejandro; Aurrecoechea, Elena; Freire, Mercedes; Tomero, Eva; Jesus Garcia-Villanueva, Maria; Stoye, Claudia; Salas-Heredia, Esteban; Antonio Bernal-Vidal, Jose; Salgado, Eva; Blanco, Ricardo; Javier Novoa, Francisco; Ibanez-Barcelo, Monica; Torrente-Segarra, Vicente; Narvaez, Javier; Calvet, Joan; Moriano Morales, Clara; Ramon Vazquez-Rodriguez, Tomas; Garcia de la Pena, Paloma; Bohorquez, Cristina; Luis Andreu-Sanchez, Jose; Cobo-Ibanez, Tatiana; Bonilla, Gema; Lozano-Rivas, Nuria; Montilla, Carlos; Javier Toyos, Francisco; Marenco De la Fuente, Jose Luis; Exposito, Lorena; Esther Ruiz-Lucea, Maria; Vals, Elia; Manero-Ruiz, Javier; Bernal-Vidal, Jose A.; Rua-Figueroa, Inigo
Abstract
Objectives. This article estimates the frequency of polyautoimmunity and associated factors in a large retrospective cohort of patients with SLE. Methods. RELESSER (Spanish Society of Rheumatology Lupus Registry) is a nationwide multicentre, hospital-based registry of SLE patients. This is a cross-sectional study. The main variable was polyautoimmunity, which was defined as the co-occurrence of SLE and another autoimmune disease, such as autoimmune thyroiditis, RA, scleroderma, inflammatory myopathy and MCTD. We also recorded the presence of multiple autoimmune syndrome, secondary SS, secondary APS and a family history of autoimmune disease. Multiple logistic regression analysis was performed to investigate possible risk factors for polyautoimmunity. Results. Of the 3679 patients who fulfilled the criteria for SLE, 502 (13.6%) had polyautoimmunity. The most frequent types were autoimmune thyroiditis (7.9%), other systemic autoimmune diseases (6.2%), secondary SS (14.1%) and secondary APS (13.7%). Multiple autoimmune syndrome accounted for 10.2% of all cases of polyautoimmunity. A family history was recorded in 11.8%. According to the multivariate analysis, the factors associated with polyautoimmunity were female sex [odds ratio (95% CI), 1.72 (1.07, 2.72)], RP [1.63 (1.29, 2.05)], interstitial lung disease [3.35 (1.84, 6.01)], Jaccoud arthropathy [1.92 (1.40, 2.63)], anti-Ro/SSA and/or anti-La/SSB autoantibodies [2.03 (1.55, 2.67)], anti-RNP antibodies [1.48 (1.16, 1.90)], MTX [1.67 (1.26, 2.18)] and antimalarial drugs [0.50 (0.38, 0.67)]. Conclusion. Patients with SLE frequently present polyautoimmunity. We observed clinical and analytical characteristics associated with polyautoimmunity. Our finding that antimalarial drugs protected against polyautoimmunity should be verified in future studies.