The protein encoded by this gene has similarity to mouse protein which is a subunit of the signal recognition particle receptor (SR). This subunit is a transmembrane GTPase belonging to the GTPase superfamily. It anchors alpha subunit, a peripheral membrane GTPase, to the ER membrane. SR is required for the cotranslational targeting of both secretory and membrane proteins to the ER membrane.
Pathway
Activation of Chaperone Genes by XBP1(S); Activation of Chaperones by IRE1alpha; Gene Expression; Metabolism of proteins; Protein export; SRP-dependent cotranslational protein targeting to membrane; Translation; Unfolded Protein Response.
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