Rabbit Anti-Human SREBF2 (a.a. 375-479) Polyclonal antibody

Antibody Isotype

IgG

Species Reactivity

Human

Immunogen

Recombinant human SREBF2 protein; Source: E. coli derived, PGEX-4T; Tag: GST; Domain: 375-479 aa of BC056158

Conjugate

Application Notes

WB: 1:1000-1:8000
IP: 0.5-4.0 μg for 1.0-3.0 mg of total protein lysate

General Notes

This product (Catalog No. DPABH-29014) is a rabbit-derived polyclonal antibody raised against human SREBF2, targeting the amino acid region 375–479 of the protein. It has been affinity purified by Protein A. SREBF2,also named as BHLHD2, is a 1141 amino acid protein, which contains 1 bHLH domain and belongs to the SREBP family. SREBF2 localizes in the endoplasmic reticulum membrane and is ubiquitously expressed in adult and fetal tissues. SREBF2 as a transcriptional activator is required for lipid homeostasis. SREBF2 expression is dynamically regulated in response to nutritional and hormonal cues. SREBF2 exists two isoform with molecular weight 124 kDa and 73 kDa.
DPABH-29014 is suitable for use in Western blot (WB) (1:1,000–1:8,000), IP (0.5-4.0 μg for 1.0-3.0 mg of total protein lysate) applications.
DPABH-29014 is supplied as a liquid formulation in PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. For long-term storage, keep at −20 °C. For short-term use, store at 2–8 °C. Avoid repeated freeze–thaw cycles to maintain antibody integrity and performance.

Alternative Names

bHLHd2; Class D basic helix-loop-helix protein 2; Processed sterol regulatory element-binding protein 2; SREBF 2; SREBP 2

Entrez Gene ID

UniProt ID