SREBF2 (AAH56158, 801 a.a. ~ 900 a.a) partial recombinant protein with GST tag. The sequence is QAFCKNLLERAIESLVKPQAKKKAGDQEEESCEFSSALEYLKLLHSFVDSVGVMSPPLSR SSVLKSALGPDIICRWWTSAITVAISWLQGDDAAVRSHFT
Conjugate
Unconjugated
Target
Alternative Names
SREBF2; sterol regulatory element binding transcription factor 2; SREBP2; bHLHd2; SREBP-2; sterol regulatory element-binding protein 2; class D basic helix-loop-helix protein 2; sterol regulatory element-binding transcription factor 2;
This gene encodes a member of the a ubiquitously expressed transcription factor that controls cholesterol homeostasis by regulating transcription of sterol-regulated genes. The encoded protein contains a basic helix-loop-helix-leucine zipper (bHLH-Zip) domain and binds the sterol regulatory element 1 motif. Alternate splicing results in multiple transcript variants.
Pathway
Activation of gene expression by SREBF (SREBP); Developmental Biology; Metabolism; PPARA activates gene expression
Citations
Publication ()
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