Fusion protein corresponding to a region derived from internal residues of human SREBF chaperone
Conjugate
Unconjugated
Applications
Application Notes
IHC: 1:25-1:100
General Notes
This product (Catalog No. DPABH-03988) is a rabbit-derived polyclonal antibody raised against human SCAP. It has been affinity purified by Protein A. This gene encodes a protein with a sterol sensing domain (SSD) and seven WD domains. In the presence of cholesterol, this protein binds to sterol regulatory element binding proteins (SREBPs) and mediates their transport from the ER to the Golgi. The SREBPs are then proteolytically cleaved and regulate sterol biosynthesis. Alternative splicing results in multiple transcript variants. DPABH-03988 is suitable for use in IHC (1:25–1:100) application. DPABH-03988 is supplied as a liquid formulation in pH7.4 PBS, 0.05% sodium azide, 40% Glycerol. For long-term storage, keep at −20 °C. For short-term use, store at 2–8 °C. Avoid repeated freeze–thaw cycles to maintain antibody integrity and performance.
Target
Alternative Names
SCAP; SREBF chaperone; sterol regulatory element-binding protein cleavage-activating protein; KIAA0199
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