Recombinant protein fragment corresponding to a region within amino acids 1 and 138 of Human RIT1 (UniProt Q92963).
Conjugate
Unconjugated
Applications
Application Notes
WB: 1/500 - 1/3000; IHC-P: 1/100 - 1/500.
Target
Alternative Names
RIT1; Ras-like without CAAX 1; Ric (Drosophila) like, expressed in many tissues; RIT; GTP-binding protein Rit1; GTP binding protein Roc1; MGC125864; MGC125865; RIBB; Ric like; expressed in many tissues; ROC1; GTP-binding protein Roc1; ras-like without CAA
Plays a crucial role in coupling NGF stimulation to the activation of both EPHB2 and MAPK14 signaling pathways and in NGF-dependent neuronal differentiation.
Pathway
NGF signalling via TRKA from the plasma membrane; Neurotrophic factor-mediated Trk receptor signaling; Signal Transduction; Signalling by NGF; Signalling to ERKs; Signalling to p38 via RIT and RIN; Trk receptor signaling mediated by the MAPK pathway
Citations
Publication ()
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COA
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