RIT1 (NP_008843, 120 a.a. ~ 217 a.a) partial recombinant protein with GST tag. The sequence is RVRRTDDTPVVLVGNKSDLKQLRQVTKEEGLALAREFSCPFFETSAAYRYYIDDVFHALV REIRRKEKEAVLAMEKKSKPKNSVWKRLKSPFRKKKDS
Conjugate
Unconjugated
Target
Alternative Names
RIT1; Ras-like without CAAX 1; NS8; RIT; RIBB; ROC1; GTP-binding protein Rit1; GTP-binding protein Roc1; ras-like without CAAX protein 1; Ric-like, expressed in many tissues; ras-like protein expressed in many tissues;
This gene encodes a member of a subfamily of Ras-related GTPases. The encoded protein is involved in regulating p38 MAPK-dependent signaling cascades related to cellular stress. This protein also cooperates with nerve growth factor to promote neuronal development and regeneration. Alternate splicing results in multiple transcript variants.
Pathway
NGF signalling via TRKA from the plasma membrane; Signal Transduction; Signalling to ERKs; Trk receptor signaling mediated by the MAPK pathway
Citations
Publication ()
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