Specifications
Species Reactivity
Mouse; Human
Immunogen
Synthetic peptide (the amino acid sequence is considered to be commercially sensitive) within Human COX2 aa 550 to the C-terminus (Cysteine residue). The exact sequence is proprietary.Database link: P35354
Applications
Application Notes
WB: 1/1000 - 1/5000; IP: 1/10 - 1/100; IHC-P: 1/250 - 1/500;
Target
Alternative Names
PTGS2; prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase); prostaglandin G/H synthase 2; COX2; PHS II; PGH synthase 2; cyclooxygenase 2b; prostaglandin H2 synthase 2; COX-2; PHS-2; PGG/HS; PGHS-2; hCox-2; GRIPGHS;
Product Background
Antigen Description
Mediates the formation of prostaglandins from arachidonate. May have a role as a major mediator of inflammation and/or a role for prostanoid signaling in activity-dependent plasticity.
Pathway
Arachidonic acid metabolism, organism-specific biosystem; Arachidonic acid metabolism, conserved biosystem; Biological oxidations, organism-specific biosystem; C-MYB transcription factor network, organism-specific biosystem; COX reactions, organism-specific biosystem; Calcineurin-regulated NFAT-dependent transcription in lymphocytes, organism-specific biosystem; Calcium signaling in the CD4+ TCR pathway, organism-specific biosystem;
Citations
Publication ()
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COA
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