Specifications
Species Reactivity
Bovine; Human; Rat
Immunogen
Recombinant protein of human PTGER2.
Applications
Application Notes
WB (1 to 5 μg/mL) & The optimal working dilution should be determined by the end user.
Target
Alternative Names
PTGER2; prostaglandin E receptor 2 (subtype EP2), 53kDa; prostaglandin E receptor 2 (subtype EP2), 53kD; prostaglandin E2 receptor EP2 subtype; EP2; prostanoid EP2 receptor; PGE receptor EP2 subtype; PGE2 receptor EP2 subtype;
Product Background
Antigen Description
Receptor for prostaglandin E2 (PGE2). The activity of this receptor is mediated by G(s) proteins that stimulate adenylate cyclase. Has a relaxing effect on smooth muscle. May play an important role in regulating renal hemodynamics, intestinal epithelial transport, adrenal aldosterone secretion, and uterine function.
Pathway
Class A/1 (Rhodopsin-like receptors), organism-specific biosystem; Eicosanoid ligand-binding receptors, organism-specific biosystem; G alpha (s) signalling events, organism-specific biosystem; GPCR downstream signaling, organism-specific biosystem; GPCR l
Citations
Publication ()
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