Anti-PTGER2 monoclonal antibody, clone 4G23

Antibody Isotype

IgG

Clone

4G23

Species Reactivity

Human; Mouse; Rat

Immunogen

Recombinant protein corresponding to human PTGER2/PTGER3.

Conjugate

Application Notes

WB (1 to 5 μg/mL) & The optimal working dilution should be determined by the end user.

Alternative Names

PTGER2; prostaglandin E receptor 2 (subtype EP2), 53kDa; prostaglandin E receptor 2 (subtype EP2), 53kD; prostaglandin E2 receptor EP2 subtype; EP2; prostanoid EP2 receptor; PGE receptor EP2 subtype; PGE2 receptor EP2 subtype;

Entrez Gene ID

UniProt ID

Antigen Description

The protein encoded by this gene is a member of the G-protein coupled receptor family. This protein is one of four receptors identified for prostaglandin E2 (PGE2). This receptor may have many biological functions, which involve digestion, nervous system, kidney reabsorption, and uterine contraction activities. Studies of the mouse counterpart suggest that this receptor may also mediate adrenocorticotropic hormone response as well as fever generation in response to exogenous and endogenous stimuli. Multiple transcript variants encoding different isoforms have been found for this gene.

Pathway

Class A/1 (Rhodopsin-like receptors), organism-specific biosystem; Eicosanoid ligand-binding receptors, organism-specific biosystem; G alpha (s) signalling events, organism-specific biosystem; GPCR downstream signaling, organism-specific biosystem; GPCR ligand binding, organism-specific biosystem; GPCRs, Class A Rhodopsin-like, organism-specific biosystem; Neuroactive ligand-receptor interaction, organism-specific biosystem;