Specifications
Species Reactivity
Mouse; Rat; Cow; Human
Immunogen
Synthetic peptide, corresponding to a cytoplasmic region near the C terminal of Human Prostaglandin E Receptor EP2 (UniProt: P43116).
Applications
Application Notes
WB: 1/1000 - 1/10000; IHC-P: 1/250 - 1/500; ICC/IF: 1/250 - 1/500; Flow Cyt: 1/100 - 1/500;
Target
Alternative Names
PTGER2; prostaglandin E receptor 2 (subtype EP2), 53kDa; prostaglandin E receptor 2 (subtype EP2), 53kD; prostaglandin E2 receptor EP2 subtype; EP2; prostanoid EP2 receptor; PGE receptor EP2 subtype; PGE2 receptor EP2 subtype;
Product Background
Antigen Description
Receptor for prostaglandin E2 (PGE2). The activity of this receptor is mediated by G(s) proteins that stimulate adenylate cyclase. The subsequent raise in intracellular cAMP is responsible for the relaxing effect of this receptor on smooth muscle.
Pathway
Class A/1 (Rhodopsin-like receptors), organism-specific biosystem; Eicosanoid ligand-binding receptors, organism-specific biosystem; G alpha (s) signalling events, organism-specific biosystem; GPCR downstream signaling, organism-specific biosystem; GPCR ligand binding, organism-specific biosystem; GPCRs, Class A Rhodopsin-like, organism-specific biosystem; Neuroactive ligand-receptor interaction, organism-specific biosystem;
Citations
Publication ()
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