Receptor for prostaglandin E2 (PGE2). The activity of this receptor is mediated by G(s) proteins that stimulate adenylate cyclase. The subsequent raise in intracellular cAMP is responsible for the relaxing effect of this receptor on smooth muscle.
Pathway
Class A/1 (Rhodopsin-like receptors); G alpha (s) signalling events; GPCR ligand binding; Inflammatory mediator regulation of TRP channels
Citations
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