Specifications
Species Reactivity
Rat; Human
Immunogen
Synthetic peptide (the amino acid sequence is considered to be commercially sensitive) corresponding to Human PKC epsilon aa 700 to the C-terminus (phospho S729).Database link: Q02156
Applications
Application Notes
WB: 1/1000 - 1/2000
Target
Alternative Names
PRKCE; protein kinase C, epsilon; protein kinase C epsilon type; PKCE; nPKC-epsilon; MGC125656; MGC125657;
Product Background
Antigen Description
This is calcium-independent, phospholipid-dependent, serine- and threonine-specific enzyme.PKC is activated by diacylglycerol which in turn phosphorylates a range of cellular proteins. PKC also serves as the receptor for phorbol esters, a class of tumor promoters.
Pathway
B Cell Receptor Signaling Pathway, organism-specific biosystem; CDC42 signaling events, organism-specific biosystem; Calcium Regulation in the Cardiac Cell, organism-specific biosystem; DAG and IP3 signaling, organism-specific biosystem; Disease, organism-specific biosystem; Downstream signal transduction, organism-specific biosystem; Downstream signaling in naive CD8+ T cells, organism-specific biosystem;
Citations
Publication ()
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COA
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