Anti-PRKCE monoclonal antibody (DCABH-433)

Mouse anti-Human PRKCE monoclonal antibody for WB, IHC-P, FC, ICC/IF Datasheet

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Specifications


Host Species
Mouse
Antibody Isotype
IgG2b
Clone
2C5
Species Reactivity
Dog, Human, Monkey
Immunogen
Recombinant full length Human PKC epsilon produced in HEK293T cells (NP_005391).
Conjugate
Unconjugated

Applications


Application Notes
WB: 1/500 - 1/2000; IHC-P: 1/150; Flow Cyt: 1/100; ICC/IF: 1/100;
*Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own experiment using appropriate negative and positive controls.

Target


Alternative Names
PRKCE; protein kinase C, epsilon; protein kinase C epsilon type; PKCE; nPKC-epsilon; MGC125656
Entrez Gene ID
UniProt ID

Product Background


Pathway
B Cell Receptor Signaling Pathway, organism-specific biosystem; CDC42 signaling events, organism-specific biosystem; Calcium Regulation in the Cardiac Cell, organism-specific biosystem; DAG and IP3 signaling, organism-specific biosystem; Disease, organism-specific biosystem; Downstream signal transduction, organism-specific biosystem; Downstream signaling in naive CD8+ T cells, organism-specific biosystem;

Citations


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References


Murray, JC; Aldeghaither, D; et al. c-Abl Modulates Tumor Cell Sensitivity to Antibody-Dependent Cellular Cytotoxicity. CANCER IMMUNOLOGY RESEARCH 2:1186-1198(2014).
Frangioudakis, G; Burchfield, JG; et al. Diverse roles for protein kinase C delta and protein kinase C epsilon in the generation of high-fat-diet-induced glucose intolerance in mice: regulation of lipogenesis by protein kinase C delta. DIABETOLOGIA 52:2616-2620(2009).

Custom Antibody Labeling


We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody. Learn More

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