Specifications
Species Reactivity
Dog; Human; Monkey
Immunogen
Recombinant full length Human PKC epsilon produced in HEK293T cells (NP_005391).
Applications
Application Notes
WB: 1/1000 - 1/2000; IHC-P: 1/150; Flow Cyt: 1/100; ICC/IF: 1/100;
Target
Alternative Names
PRKCE; protein kinase C, epsilon; protein kinase C epsilon type; PKCE; nPKC-epsilon; MGC125656; MGC125657;
Product Background
Antigen Description
This is calcium-independent, phospholipid-dependent, serine- and threonine-specific enzyme.PKC is activated by diacylglycerol which in turn phosphorylates a range of cellular proteins. PKC also serves as the receptor for phorbol esters, a class of tumor promoters.
Pathway
B Cell Receptor Signaling Pathway, organism-specific biosystem; CDC42 signaling events, organism-specific biosystem; Calcium Regulation in the Cardiac Cell, organism-specific biosystem; DAG and IP3 signaling, organism-specific biosystem; Disease, organism-specific biosystem; Downstream signal transduction, organism-specific biosystem; Downstream signaling in naive CD8+ T cells, organism-specific biosystem;
Citations
Publication ()
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COA
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