Anti-PPP2R5B polyclonal antibody (DPABH-06605)

Mouse Anti-Human PPP2R5B (full length) polyclonal antibody for WB

Specifications


Host Species
Mouse
Antibody Isotype
IgG
Species Reactivity
Human
Immunogen
Recombinant full length protein corresponding to amino acids 1-497 of Human PPP2R5B (NP_006235.1).
Conjugate
Unconjugated

Applications


Application Notes
WB: 1 μg/ml.
*Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own experiment using appropriate negative and positive controls.

Target


Alternative Names
PPP2R5B; protein phosphatase 2, regulatory subunit B, beta; protein phosphatase 2, regulatory subunit B (B56), beta isoform; protein phosphatase 2, regulatory subunit B, beta isoform; serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit beta
Entrez Gene ID
UniProt ID

Product Background


Pathway
Activation of Chaperone Genes by XBP1(S); Activation of Chaperones by IRE1alpha; Adaptive Immune System; Beta-catenin phosphorylation cascade; CTLA4 inhibitory signaling; Cell Cycle; Cell Cycle, Mitotic

Citations


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Custom Antibody Labeling


We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody. Learn More

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References


Association between CAG repeat length in the PPP2R2B gene and Alzheimer disease in the Japanese population

NEUROSCIENCE LETTERS

Authors: Kimura, Ryo; Morihara, Takashi; Kudo, Takashi; Kamino, Kouzin; Takeda, Masatoshi

We analyzed the association between PPP2R2B gene CAG repeat length and Alzheimer disease (AD) susceptibility in the Japanese population. Blood samples were collected from 218 late-onset AD patients and 86 controls. DNA fragments containing the target GAG repeat region were amplified using polymerase chain reaction (PCR). PCR products were sequenced using ABI PRISM 310 genetic analyzer. The mean CAG repeat length did not differ significantly between the control and AD groups. In contrast, the frequency of CAG repeats shorter than 15 was significantly higher in AD group, specifically in the AD with APOE4 subgroup, than in the control group. The results suggest that CAG repeat lengths in the PPP2R2B gene may be potential genetic markers for AD susceptibility in the Japanese population. (C) 2010 Elsevier Ireland Ltd. All rights reserved.

Mapping of the PPP2R2B gene to canine chromosome 2q4.3 by fluorescence in situ hybridization and confirmation by radiation hybrid mapping

ANIMAL GENETICS

Authors: Kuiper, H; Drogemuller, C; Guyon, R; Andre, C; Distl, O

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