Specifications
Immunogen
Synthetic peptide: KYFAQEALTVLSLA, corresponding to C terminal amino acids 576-589 of Human PPP2R1A (UniProt ID: P30153).
Applications
Application Notes
WB: 0.03 - 0.1 μg/ml; IHC-P: 3.75 μg/ml; ELISA: 1/8000.
Target
Alternative Names
PPP2R1A; protein phosphatase 2, regulatory subunit A, alpha; protein phosphatase 2 (formerly 2A), regulatory subunit A (PR 65), alpha isoform; protein phosphatase 2 (formerly 2A), regulatory subunit A, alpha isoform; serine/threonine-protein phosphatase 2
Product Background
Antigen Description
The PR65 subunit of protein phosphatase 2A serves as a scaffolding molecule to coordinate the assembly of the catalytic subunit and a variable regulatory B subunit. Required for proper chromosome segregation and for centromeric localization of SGOL1 in mitosis.
Pathway
Activated TLR4 signalling; Adaptive Immune System; Beta-catenin phosphorylation cascade; CTLA4 inhibitory signaling; Canonical Wnt signaling pathway; Cell Cycle; Cell Cycle, Mitotic
Citations
Publication ()
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COA
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