Anti-PPP2R1A (aa 7-19) polyclonal antibody

Species Reactivity

Bovine; Human; Mouse; Rat

Immunogen

A synthetic peptide (conjugated with KLH ) corresponding to amino acids 7-19 of PPP2R1A. The sequence is DDSLYPIAVLIDE

Conjugate

Application Notes

WB: 1 to 5 ug; Immunocy to chemistry: 1:500 to 1:1000. & The optimal working dilution should be determined by the end user.

Alternative Names

PPP2R1A; protein phosphatase 2, regulatory subunit A, alpha; PR65A; PP2AAALPHA; PP2A-Aalpha; serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform; PP2A subunit A isoform R1-alpha; PP2A subunit A isoform PR65-alpha; medium tumo

Entrez Gene ID

UniProt ID

Antigen Description

This gene encodes a constant regulatory subunit of protein phosphatase 2. Protein phosphatase 2 is one of the four major Ser/Thr phosphatases, and it is implicated in the negative control of cell growth and division. It consists of a common heteromeric core enzyme, which is composed of a catalytic subunit and a constant regulatory subunit, that associates with a variety of regulatory subunits. The constant regulatory subunit A serves as a scaffolding molecule to coordinate the assembly of the catalytic subunit and a variable regulatory B subunit. This gene encodes an alpha isoform of the constant regulatory subunit A. Alternatively spliced transcript variants have been described.

Pathway

AMPK signaling pathway; Activated TLR4 signalling; Adrenergic signaling in cardiomyocytes; Beta-catenin phosphorylation cascade