Anti-PON1 (aa 246-355) polyclonal antibody

Species Reactivity

Human

Immunogen

PON1 (NP_000437, 246 a.a. ~ 355 a.a) partial recombinant protein with GST tag. The sequence is HVYEKHANWTLTPLKSLDFNTLVDNISVDPETGDLWVGCHPNGMKIFFYDSENPPASEVL RIQNILTEEPKVTQVYAENGTVLQGSTVASVYKGKLLIGTVFHKALYCEL

Conjugate

Alternative Names

PON1; paraoxonase 1; ESA; PON; MVCD5; serum paraoxonase/arylesterase 1; K-45; PON 1; esterase A; A-esterase 1; arylesterase 1; paraoxonase B-type; aromatic esterase 1; arylesterase B-type; serum aryldiakylphosphatase; serum aryldialkylphosphatase 1;

Entrez Gene ID

UniProt ID

Antigen Description

The enzyme encoded by this gene is an arylesterase that mainly hydrolyzes paroxon to produce p-nitrophenol. Paroxon is an organophosphorus anticholinesterase compound that is produced in vivo by oxidation of the insecticide parathion. Polymorphisms in this gene are a risk factor in coronary artery disease. The gene is found in a cluster of three related paraoxonase genes at 7q21.3.

Pathway

Phase I, non P450;