DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Component of RNA polymerase II which synthesizes mRNA precursors and many functional non-coding RNAs. Pol II is the central component of the basal RNA polymerase II transcription machinery. It is composed of mobile elements that move relative to each other. RPB3 is part of the core element with the central large cleft and the clamp element that moves to open and close the cleft.
Pathway
Abortive elongation of HIV-1 transcript in the absence of Tat; DNA Repair; Disease; Dual incision reaction in TC-NER; Eukaryotic Transcription Initiation; Formation of HIV-1 elongation complex containing HIV-1 Tat; Formation of HIV-1 elongation complex in
Custom Antibody Labeling
We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody. Learn More
Citations
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Park, JH; Kim, NS; et al. MGMT-535G > T polymorphism is associated with prognosis for patients with metastatic colorectal cancer treated with oxaliplatin-based chemotherapy. JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY 136:1135-1142(2010).
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COA
Certificate of Analysis