Synthetic peptide (the amino acid sequence is considered to be commercially sensitive) within Human POLR2C aa 200 to the C-terminus. The exact sequence is proprietary.Database link: P19387
Conjugate
Unconjugated
Applications
Application Notes
WB: 1/1000 - 1/2000;
Target
Alternative Names
POLR2C; polymerase (RNA) II (DNA directed) polypeptide C, 33kDa; polymerase (RNA) II (DNA directed) polypeptide C (33kD); DNA-directed RNA polymerase II subunit RPB3; RNA polymerase II subunit 3; RPB3; RPB33; RNA polymerase II subunit B3; DNA-directed RNA
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Component of RNA polymerase II which synthesizes mRNA precursors and many functional non-coding RNAs. Pol II is the central component of the basal RNA polymerase II transcription machinery. It is composed of mobile elements that move relative to each other. RPB3 is part of the core element with the central large cleft and the clamp element that moves to open and close the cleft.
Pathway
Abortive elongation of HIV-1 transcript in the absence of Tat, organism-specific biosystem; DNA Repair, organism-specific biosystem; Disease, organism-specific biosystem; Dual incision reaction in TC-NER, organism-specific biosystem; Eukaryotic Transcription Initiation, organism-specific biosystem; Formation of HIV-1 elongation complex containing HIV-1 Tat, organism-specific biosystem; Formation of HIV-1 elongation complex in the absence of HIV-1 Tat, organism-specific biosystem;
Custom Antibody Labeling
We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody. Learn More
Citations
Have you cited DCABH-7171 in a publication? Let us know and earn a reward for your research.
Park, JH; Kim, NS; et al. MGMT-535G > T polymorphism is associated with prognosis for patients with metastatic colorectal cancer treated with oxaliplatin-based chemotherapy. JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY 136:1135-1142(2010).
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COA
Certificate of Analysis