Anti-PLIN1 monoclonal antibody Made to order

Antibody Isotype

IgG

Species Reactivity

Human

Immunogen

A synthetic peptide of human PLIN is used for rabbit immunization.

Conjugate

Alternative Names

PLIN1; perilipin 1; PERI; PLIN; FPLD4; perilipin-1; lipid droplet-associated protein;

Entrez Gene ID

UniProt ID

Antigen Description

The protein encoded by this gene coats lipid storage droplets in adipocytes, thereby protecting them until they can be broken down by hormone-sensitive lipase. The encoded protein is the major cAMP-dependent protein kinase substrate in adipocytes and, when unphosphorylated, may play a role in the inhibition of lipolysis. Alternatively spliced transcript variants varying in the 5 UTR, but encoding the same protein, have been found for this gene.

Pathway

Adipogenesis; Developmental Biology; Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis; Lipid digestion, mobilization, and transport; Metabolism; Metabolism of lipids and lipoproteins; PPAR signaling pathway; Transcriptional Regulation of White Adipocyte Differentiation;