Anti-PAX4 (aa 121-217) polyclonal antibody

Species Reactivity

Human

Immunogen

PAX4 (NP_006184, 121 a.a. ~ 217 a.a) partial recombinant protein with GST tag. The sequence is RALQEDQGLPCTRLRSPAVLAPAVLTPHSGSETPRGTHPGTGHRNRTIFSPSQAEALEKE FQRGQYPDSVARGKLATATSLPEDTVRVWFSNRRAKW

Conjugate

Alternative Names

PAX4; paired box 4; KPD; MODY9; paired box protein Pax-4; paired box gene 4; paired domain gene 4;

Entrez Gene ID

UniProt ID

Antigen Description

This gene is a member of the paired box (PAX) family of transcription factors. Members of this gene family typically contain a paired box domain, an octapeptide, and a paired-type homeodomain. These genes play critical roles during fetal development and cancer growth. The paired box 4 gene is involved in pancreatic islet development and mouse studies have demonstrated a role for this gene in differentiation of insulin-producing beta cells.

Pathway

Developmental Biology; Maturity onset diabetes of the young; Regulation of gene expression in endocrine-committed (NEUROG3+) progenitor cells;