Anti-PAX4 monoclonal antibody, clone 4D23

Clone

4D23

Species Reactivity

Human

Immunogen

Recombinant protein corresponding to human PAX4.

Conjugate

Application Notes

ELISA (1:10000); WB (1:500-1:2000) & The optimal working dilution should be determined by the end user.

Alternative Names

PAX4; paired box 4; paired box gene 4; paired box protein Pax-4; MODY9; paired domain gene 4; KPD; MGC129960;

Entrez Gene ID

UniProt ID

Antigen Description

This gene is a member of the paired box (PAX) family of transcription factors. Members of this gene family typically contain a paired box domain, an octapeptide, and a paired-type homeodomain. These genes play critical roles during fetal development and cancer growth. The paired box 4 gene is involved in pancreatic islet development and mouse studies have demonstrated a role for this gene in differentiation of insulin-producing beta cells.

Pathway

Developmental Biology, organism-specific biosystem; Maturity onset diabetes of the young, organism-specific biosystem; Maturity onset diabetes of the young, conserved biosystem; Regulation of beta-cell development, organism-specific biosystem; Regulation of gene expression in endocrine-committed (NEUROG3+) progenitor cells, organism-specific biosystem;