General Notes
This product (Catalog No. DPABH-00598) is a rabbit-derived IgG polyclonal antibody raised against human PA2G4. This antibody exhibits cross-reactivity with PA2G4 from mouse and rat. It has been affinity purified by protein A. This gene encodes an RNA-binding protein that is involved in growth regulation. This protein is present in pre-ribosomal ribonucleoprotein complexes and may be involved in ribosome assembly and the regulation of intermediate and late steps of rRNA processing. This protein can interact with the cytoplasmic domain of the ErbB3 receptor and may contribute to transducing growth regulatory signals. This protein is also a transcriptional co-repressor of androgen receptor-regulated genes and other cell cycle regulatory genes through its interactions with histone deacetylases. This protein has been implicated in growth inhibition and the induction of differentiation of human cancer cells. Six pseudogenes, located on chromosomes 3, 6, 9, 18, 20 and X, have been identified.
DPABH-00598 is suitable for use in Western blot (WB) (1:500–1:2,000), IHC (1:50–1:100), IF (immunofluorescence) (1:50–1:100) applications.
DPABH-00598 is supplied as a liquid formulation in PBS with 0.02% sodium azide, 50% glycerol, pH7.3. For long-term storage, keep at −20 °C. For short-term use, store at 2–8 °C. Avoid repeated freeze–thaw cycles to maintain antibody integrity and performance.
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