Specifications
Immunogen
Recombinant fragment, corresponding to a region within amino acids 2-275 of Human MMP3 (Uniprot ID: P08254).
Applications
Application Notes
WB: 1/500 - 1/3000; IHC-P: 1/100 - 1/1000.
Target
Alternative Names
MMP3; matrix metallopeptidase 3 (stromelysin 1, progelatinase); matrix metalloproteinase 3 (stromelysin 1, progelatinase); STMY, STMY1; stromelysin-1; transin-1; proteoglycanase; matrix metalloproteinase-3; matrix metalloproteinase 3 (stromelysin 1, proge
Product Background
Antigen Description
Can degrade fibronectin, laminin, gelatins of type I, III, IV, and V; collagens III, IV, X, and IX, and cartilage proteoglycans. Activates procollagenase.
Pathway
Activation of Matrix Metalloproteinases; Degradation of the extracellular matrix; Extracellular matrix organization; Matrix Metalloproteinases; Rheumatoid arthritis; Transcriptional misregulation in cancer;
Citations
Publication ()
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COA
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