Specifications
Species Reactivity
Mouse; Human
Immunogen
Recombinant full length human MNK1 protein (AAH02755) linked to a proprietary tag.
Applications
Application Notes
Flow Cyt: 1μg/106 cells; WB: 1 - 5 μg/ml; IHC-P: 3 μg/ml; ICC/IF: 10 μg/ml.
Target
Alternative Names
MKNK1; MAP kinase interacting serine/threonine kinase 1; MAP kinase-interacting serine/threonine-protein kinase 1; MNK1; MAPK signal-integrating kinase 1; MAP kinase signal-integrating kinase 1;
Product Background
Antigen Description
May play a role in the response to environmental stress and cytokines. Appears to regulate transcription by phosphorylating EIF4E, thus increasing the affinity of this protein for the 7-methylguanosine-containing mRNA cap.
Pathway
IL-2 Signaling Pathway, organism-specific biosystem; Insulin signaling pathway, organism-specific biosystem; Insulin signaling pathway, conserved biosystem; MAPK signaling pathway, organism-specific biosystem; MAPK signaling pathway, conserved biosystem; Negative regulation of FGFR signaling, organism-specific biosystem; Signal Transduction, organism-specific biosystem;
Citations
Publication ()
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COA
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