Does not bind DNA by itself. Recruits histone deacetylases and DNA methyltransferases. Acts as transcriptional repressor and plays a role in gene silencing.
Pathway
Gene Expression; RNA Polymerase I Promoter Clearance; RNA Polymerase I Transcription; RNA Polymerase I Transcription Initiation; RNA Polymerase I, RNA Polymerase III, and Mitochondrial Transcription; Signaling events mediated by HDAC Class I
Citations
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