Specifications
Immunogen
Recombinant protein corresponding to human LPL.
Applications
Application Notes
ELISA (1:10000); WB (1:500-1:2000); The optimal working dilution should be determined by the end user.
Target
Alternative Names
LPL; lipoprotein lipase; LIPD; HDLCQ11;
Product Background
Antigen Description
LPL encodes lipoprotein lipase, which is expressed in heart, muscle, and adipose tissue. LPL functions as a homodimer, and has the dual functions of triglyceride hydrolase and ligand/bridging factor for receptor-mediated lipoprotein uptake. Severe mutations that cause LPL deficiency result in type I hyperlipoproteinemia, while less extreme mutations in LPL are linked to many disorders of lipoprotein metabolism.
Pathway
Adipogenesis, organism-specific biosystem; Alzheimers disease, organism-specific biosystem; Alzheimers disease, conserved biosystem; Chylomicron-mediated lipid transport, organism-specific biosystem; Developmental Biology, organism-specific biosystem; Fatty Acid Beta Oxidation, organism-specific biosystem; Glycerolipid metabolism, organism-specific biosystem;
Citations
Publication ()
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COA
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