Specifications
Immunogen
Synthetic peptide (the amino acid sequence is considered to be commercially sensitive) within Human Lipoprotein lipase aa 450 to the C-terminus (Cysteine residue). The exact sequence is proprietary.Database link: P06858
Applications
Application Notes
WB: 1/10000 - 1/50000; IHC-P: 1/250 - 1/500
Target
Alternative Names
LPL; lipoprotein lipase; LIPD; HDLCQ11;
Product Background
Antigen Description
The primary function of this lipase is the hydrolysis of triglycerides of circulating chylomicrons and very low density lipoproteins (VLDL). Binding to heparin sulfate proteogylcans at the cell surface is vital to the function. The apolipoprotein, APOC2, acts as a coactivator of LPL activity in the presence of lipids on the luminal surface of vascular endothelium.
Pathway
Adipogenesis, organism-specific biosystem; Alzheimers disease, organism-specific biosystem; Alzheimers disease, conserved biosystem; Chylomicron-mediated lipid transport, organism-specific biosystem; Developmental Biology, organism-specific biosystem; Fatty Acid Beta Oxidation, organism-specific biosystem; Glycerolipid metabolism, organism-specific biosystem;
Citations
Publication ()
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COA
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