Specifications
Immunogen
Recombinant full length Human Lipoprotein lipase (amino acids 28-475) produced in HEK293T cells (NP_000228).
Applications
Application Notes
WB: 1/2000; IHC-P: 1/150; ICC/IF: 1/100
Target
Alternative Names
LPL; lipoprotein lipase; LIPD; HDLCQ11;
Product Background
Antigen Description
The primary function of this lipase is the hydrolysis of triglycerides of circulating chylomicrons and very low density lipoproteins (VLDL). Binding to heparin sulfate proteogylcans at the cell surface is vital to the function. The apolipoprotein, APOC2, acts as a coactivator of LPL activity in the presence of lipids on the luminal surface of vascular endothelium.
Pathway
Adipogenesis, organism-specific biosystem; Alzheimers disease, organism-specific biosystem; Alzheimers disease, conserved biosystem; Chylomicron-mediated lipid transport, organism-specific biosystem; Developmental Biology, organism-specific biosystem; Fatty Acid Beta Oxidation, organism-specific biosystem; Glycerolipid metabolism, organism-specific biosystem;
Citations
Publication ()
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