Specifications
Species Reactivity
Mouse; Rat; Human
Immunogen
Synthetic peptide (the amino acid sequence is considered to be commercially sensitive) within Human LOX aa 350 to the C-terminus (Cysteine residue). The exact sequence is proprietary.Database link: P28300
Applications
Application Notes
WB: 1/1000 - 1/10000, unpurified: 1/1000 - 1/2000; IHC-P: 1/900, unpurified: 1/300; ICC/IF: 1/300, unpurified: 1/100; IP: 1/10 - 1/100; Flow Cyt: 1/90, unpurified: 1/30;
Target
Alternative Names
LNX1; ligand of numb-protein X 1, E3 ubiquitin protein ligase; ligand of numb protein X , ligand of numb protein X 1 , LNX; E3 ubiquitin-protein ligase LNX; MPDZ; PDZRN2; numb-binding protein 1; PDZ domain-containing ring finger protein 2; multi-PDZ-doma
Product Background
Antigen Description
Responsible for the post-translational oxidative deamination of peptidyl lysine residues in precursors to fibrous collagen and elastin. In addition to cross-linking of extracellular matrix proteins, may have a direct role in tumor suppression.
Pathway
Notch signaling pathway, organism-specific biosystem;
Citations
Publication ()
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