Anti-LNX1 monoclonal antibody (DCABH-652)

Mouse anti-Human LOX monoclonal antibody for FC, ICC/IF Datasheet

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Specifications


Host Species
Mouse
Antibody Isotype
IgG1
Clone
0C6
Species Reactivity
Human
Immunogen
Recombinant fragment, corresponding to amino acids 22-168 of Human LOX produced in HEK293T cells, (NP_002308).
Conjugate
Unconjugated

Applications


Application Notes
Flow Cyt: 1/100; ICC/IF: 1/100.
*Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own experiment using appropriate negative and positive controls.

Target


Alternative Names
LNX1; ligand of numb-protein X 1, E3 ubiquitin protein ligase; ligand of numb protein X , ligand of numb protein X 1 , LNX; E3 ubiquitin-protein ligase LNX; MPDZ; PDZRN2
Entrez Gene ID
UniProt ID

Product Background


Pathway
Notch signaling pathway, organism-specific biosystem;

Citations


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References


Takahashi, S; Iwamoto, N; et al. The E3 ubiquitin ligase LNX1p80 promotes the removal of claudins from tight junctions in MDCK cells. JOURNAL OF CELL SCIENCE 122:985-994(2009).
Zheng, D; Sun, YQ; et al. LNX (Ligand of Numb-protein X) interacts with RhoC, both of which regulate AP-1-mediated transcriptional activation. MOLECULAR BIOLOGY REPORTS 37:2431-2437(2010).

Custom Antibody Labeling


We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody. Learn More

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