Anti-PSA monoclonal antibody, clone B093

Antibody Isotype

IgG2a

Clone

B093

Species Reactivity

Human

Immunogen

Human PSA

Conjugate

Application Notes

ELISA, Pr
We recommend the following for sandwich ELISA (Capture - Detection):
DMABT-H4157MH - DMABT-H4166MH

Alternative Names

KLK3; kallikrein-related peptidase 3; APS, kallikrein 3, (prostate specific antigen); prostate-specific antigen; PSA; seminin; P-30 antigen; kallikrein-3; semenogelase; gamma-seminoprotein; prostate specific antigen; APS; hK3; KLK2A1;

Entrez Gene ID

UniProt ID

Antigen Description

Prostate-specific antigen (PSA), also known as gamma-seminoprotein or kallikrein-3 (KLK3), is a glycoprotein encoded in humans by the KLK3 gene. PSA is a member of the kallikrein-related peptidase family and is secreted by the epithelial cells of the prostate gland. PSA is produced for the ejaculate, where it liquefies semen in the seminal coagulum and allows sperm to swim freely. It is also believed to be instrumental in dissolving cervical mucus, allowing the entry of sperm into the uterus.

Pathway

Coregulation of Androgen receptor activity, organism-specific biosystem; Diabetes pathways, organism-specific biosystem; Disease, organism-specific biosystem; FOXA1 transcription factor network, organism-specific biosystem; Pathways in cancer, organism-specific biosystem; Prostate cancer, organism-specific biosystem; Prostate cancer, conserved biosystem;