Anti-IgG2 monoclonal antibody [HRP] (CABT-48869MH)

Mouse anti-Human IgG2 monoclonal antibody for IHC-Fr, ELISA. Datasheet

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Specifications


Host Species
Mouse
Antibody Isotype
IgG1
Clone
HP6014
Species Reactivity
Human
Conjugate
HRP

Target


Alternative Names
IgG2; IGHG2; Immunoglobulin G; G2m marker; Ig gamma 2 chain C region; Immunoglobulin G
Entrez Gene ID
UniProt ID
P01859

Product Background


Pathway
Classical antibody-mediated complement activation; Complement cascade; Creation of C4 and C2 activators; FCGR activation; Fcgamma receptor (FCGR) dependent phagocytosis; Immune System; Initial triggering of complement; Innate Immune System; Regulation of actin dynamics for phagocytic cup formation; Role of phospholipids in phagocytosis;

Citations


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References


Beck, A; Wagner-Rousset, E; et al. Therapeutic antibodies and related products: choosing the right structure for success. M S-MEDECINE SCIENCES 25:1024-1032(2009).
Ferrari, S; Palavra, K; et al. Persistence of circulating ADAMTS13-specific immune complexes in patients with acquired thrombotic thrombocytopenic purpura. HAEMATOLOGICA 99:779-787(2014).

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