Anti-IgG2 monoclonal antibody [HRP] (CABT-48869MH)

Mouse anti-Human IgG2 monoclonal antibody for IHC-Fr, ELISA. Datasheet

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Specifications


Host Species
Mouse
Antibody Isotype
IgG1
Clone
HP6014
Species Reactivity
Human
Conjugate
HRP

Target


Alternative Names
IgG2; IGHG2; Immunoglobulin G; G2m marker; Ig gamma 2 chain C region; Immunoglobulin G
Entrez Gene ID
UniProt ID
P01859

Product Background


Pathway
Classical antibody-mediated complement activation; Complement cascade; Creation of C4 and C2 activators; FCGR activation; Fcgamma receptor (FCGR) dependent phagocytosis; Immune System; Initial triggering of complement; Innate Immune System; Regulation of actin dynamics for phagocytic cup formation; Role of phospholipids in phagocytosis;

Citations


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References


Corscadden, KJ; Kirkham, LAS; et al. High pneumococcal serotype specific IgG, IgG1 and IgG2 levels in serum and the middle ear of children with recurrent acute otitis media receiving ventilation tubes. VACCINE 31:1393-1399(2013).
Bruschi, M; Sinico, RA; et al. Glomerular Autoimmune Multicomponents of Human Lupus Nephritis In Vivo: alpha-Enolase and Annexin Al. JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY 25:2483-2498(2014).

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